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Table 4 Reproductive history and related endogenous exposures

From: Hormonal exposures and the risk of intracranial meningioma in women: a population-based case-control study

Exposure* Cases n Controls n OR (95% CI)†
Age at menarche
< 12 22 44 Referent
12 – 14 100 212 0.9 (0.5 – 1.7)
> 14 21 30 1.2 (0.6 – 2.7)
Number of live births
None 18 58 Referent
1 22 28 2.0 (0.9 – 4.6)
≥ 2 103 200 1.4 (0.7 – 2.6)
Age at first birth
< 20 25 44 Referent
20 – 29 86 159 1.2 (0.6 – 2.4)
≥ 30 14 25 1.2 (0.4 – 3.8)
Ever Breast Feeding
No 57 75 Referent
Yes 71 154 0.7 (0.4 – 1.0)
Menstrual status on reference date**
Menstruating 21 72 Referent
Post-menopausal and not using HRT 38 58 2.8 (1.1 – 7.1)
Menstrual status 10 years before reference date**
Menstruating 35 83 Referent
Post-menopausal and not using HRT 23 46 0.6 (0.2 – 1.9)
  1. * Reported exposure before reference date, which for a case and her two matched controls was the date the case had surgery for her meningioma.
  2. † Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable conditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.
  3. ** Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable unconditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables.