Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Angiostatin generating capacity and anti-tumour effects of D-penicillamine and plasminogen activators

Figure 1

In vitro angiostatin generation by tPA and D-penicillamine. Murine serum was incubated with tPA, D-penicillamine, or a combination of the two. Reaction products were subjected to Western blot analysis employing an anti-mouse plasminogen antibody. In control samples (a) or samples incubated with D-penicillamine (c), no conversion of plasminogen could be demonstrated. Incubation of serum with tPA resulted in the formation of plasmin and a small amount of angiostatin (b), whereas substantial amounts of angiostatin were observed after incubating serum with both tPA and D-penicillamine (d). PLG: plasminogen PLM: plasmine ANG: angiostatin

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us