Prognostic significance of cyclooxygenase-2 (COX-2) expression in patients with surgically resectable adenocarcinoma of the oesophagus

Table 1 Univariate and Multivariate analysis of survival related clinicopathologic parameters by the Cox Proportional Hazards Model

	Univariate			Multivariate
n = 90	RR	95% CI	p-value	RR	95% CI	p-value
Age	1.01	0.98 – 1.03	0.620	1.02	0.99 – 1.04	0.120
Male gender	0.85	0.40 – 1.78	0.660	1.51	0.69 – 3.28	0.300
Higher T-stage (>T2)	2.79	1.41 – 5.51	0.003	2.25	0.92 – 5.14	0.060
Higher N-stage (>N0)	2.96	1.58 – 5.54	<0.001	2.30	1.25 – 4.23	0.010
Poorly differentiated tumour	1.78	0.94 – 3.36	0.077	1.53	0.73 – 3.20	0.260
High COX-2 score (≥200)	3.53	2.11 – 5.89	<0.001	2.91	1.78 – 4.76	<0.001

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