Figure 2From: Somatic VHLgene alterations in MEN2-associated medullary thyroid carcinoma LOH analysis of the VHL gene locus of 3 cases of MEN 2A-related MTCs with marker D3S1038 or D3S1110. All cases show loss of one allele in microdissected tumor tissue (T), whereas heterozygosity is retained in normal non-neoplastic tissue (N). Arrows indicate the 2 VHL alleles.Back to article page