Skip to main content

Table 4 Growth progression of MM-B1 cell line after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

Days after implantation 38 45 52 59 66 73
Mediastinum nodules < 101 10–201 10–202 10–202 >203 >203
Pericardium nodules < 101 10–201 10–202 10–202 >203 >203
Parietal Pleura nodules - - - 10–202 >203 >203
Lungs nodules - - - 10–202 >203 >203
Diaphragms nodules - - - - - -
  1. 2 × 106 MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times, mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.
  2. 1 Nodule diameter ≤ 1 mm; 2 Nodule diameter 2–3 mm; 3 Nodule diameter ≥ 3 mm. No nodules were found before the days indicated in the table.