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Table 4 Growth progression of MM-B1 cell line after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

Days after implantation

38

45

52

59

66

73

Mediastinum nodules

< 101

10–201

10–202

10–202

>203

>203

Pericardium nodules

< 101

10–201

10–202

10–202

>203

>203

Parietal Pleura nodules

-

-

-

10–202

>203

>203

Lungs nodules

-

-

-

10–202

>203

>203

Diaphragms nodules

-

-

-

-

-

-

  1. 2 × 106 MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times, mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.
  2. 1 Nodule diameter ≤ 1 mm; 2 Nodule diameter 2–3 mm; 3 Nodule diameter ≥ 3 mm. No nodules were found before the days indicated in the table.