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Table 3 Growth progression of IST-Mes3/2P cell line after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

Days after implantation

54

61

68

75

82

89

Mediastinum nodules

< 101

<102

<103

<103

10–203

10–203

Pericardium nodules

< 101

<102

<103

<103

10–203

10–203

Parietal Pleura nodules

< 101

<102

<103

<103

10–203

10–203

Lungs nodules

 

-

-

-

<102

<102

Diaphragms nodules

-

-

-

-

<102

<102

  1. 2 × 106 IST-Mes3/2P cells were injected into the pleural cavity of nude mice. At indicated times mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.
  2. 1 Nodule diameter ≤ 1 mm; 2 Nodule diameter = 2–3 mm; 3 Nodule diameter ≥ 3. No nodules were found before the days indicated in the table.