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Table 3 Growth progression of IST-Mes3/2P cell line after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

Days after implantation 54 61 68 75 82 89
Mediastinum nodules < 101 <102 <103 <103 10–203 10–203
Pericardium nodules < 101 <102 <103 <103 10–203 10–203
Parietal Pleura nodules < 101 <102 <103 <103 10–203 10–203
Lungs nodules   - - - <102 <102
Diaphragms nodules - - - - <102 <102
  1. 2 × 106 IST-Mes3/2P cells were injected into the pleural cavity of nude mice. At indicated times mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.
  2. 1 Nodule diameter ≤ 1 mm; 2 Nodule diameter = 2–3 mm; 3 Nodule diameter ≥ 3. No nodules were found before the days indicated in the table.