Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines

Table 1 Statistical results comparing the trypan blue live-cell means of the tococpherol-treated sampleswith vehicle-treated sample at 48 and 72 hours following 100 μM tocopherol treatment

	SW480		HCT-15		HCT-116		HT-29		CCD-112CoN
Treatment Agent	p-value 48 hour	p-value 72 hour	p-value 48 hour	p-value 72 hour	p-value 48 hour	p-value 72 hour	p-value 48 hour	p-value 72 hour	p-value 72 hour
alpha tocopherol	0.034	<0.001	0.775	<0.0001	0.996	0.084	0.000	<0.0001	0.020
gamma tocopherol	0.0001	<0.001	0.112	<0.0001	0.0005	0.005	<0.0001	<0.0001	0.927
15-deoxy Δ12, 14 PGJ₂	0.0004	<0.001	N/A	N/A	N/A	N/A	N/A	N/A	N/A
troglitazone	N/A	N/A	N/A	N/A	0.0003	0.0005	0.0000	<0.0001	<0.0001
camptothecin	N/A	N/A	0.853	<0.001	N/A	N/A	N/A	N/A	N/A
alpha vs. gamma	<0.018	<0.001	0.416	<0.001	0.0005	0.001	0.0000	<0.0001	0.0117

*Comparison of means was performed using one-way anova and a Tukey's post hoc analysis. Data are representative of three independent trials performed in triplicate.

ISSN: 1471-2407