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Table 4 Toxicity-related treatment modifications

From: Weekly oxaliplatin, 5-fluorouracil and folinic acid (OXALF) as first-line chemotherapy for elderly patients with advanced gastric cancer: results of a phase II trial

Treatment modifications

No. of patients

%

Any dose reduction

18

42.8%

Any cycle delay

20

47.6%

Toxicity-related withdrawals

3

7.1%

Time to treatment modification

Months

Range

Median time to reduction

2.0

1.0–5.3

Median time to first delay

1.3

0.5–3

Median time to toxicity-related withdrawal

3.9

1.8–6.0