Figure 2From: Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy Induction of apoptosis by 5-flurouracil. HCT116 cells were cultured for 72 h in the presence of 5-FU. Grey bars: wild type. Black bars: knock-out mutants. Upper panel p53-/-, middle panel p21CIP/WAF-1-/-, lower panel Bax -/-. *: p < 0.05, **: p < 0.005.Back to article page