Table 3 Toxicity
Hematological Toxicity | Gr1 | Gr2 | Gr3 | Gr4 | ≧Gr3 (%) | Over all (%) |
|---|---|---|---|---|---|---|
anemia | 0 | 11 | 0 | 0 | 0 (0) | 11 (26.2) |
leukopenia | 0 | 1 | 0 | 0 | 1 (0) | 1 (2.3) |
thrombocytopenia | 0 | 2 | 3 | 0 | 3 (7.1) | 5 (11.9) |
Non-hematological Toxicity | Gr1 | Gr2 | Gr3 | Gr4 | ≧Gr3 (%) | Over all (%) |
nausea | 3 | 4 | 1 | 0 | 1 (2.3) | 8 (19.0) |
vomiting | 1 | 1 | 3 | 0 | 1 (2.3) | 5 (11.9) |
appetite loss | 0 | 0 | 6 | 0 | 6 (14.3) | 6 (14.3) |
oral mucositis | 0 | 4 | 0 | 0 | 0 (0) | 4 (9.5) |
taste disturbance | 0 | 1 | 0 | 0 | 1 (2.3) | 1 (2.3) |
upper GI tract bleeding | 0 | 1 | 0 | 0 | 0 (0) | 1 (2.3) |
diarrhea | 1 | 0 | 0 | 0 | 0 (0) | 1 (2.3) |
general fatigue | 0 | 1 | 1 | 0 | 1 (2.3) | 2 (4.7) |
jaundice | 0 | 0 | 4 | 0 | 4 (9.5) | 4 (9.5) |
serum AST/ALT level elevation | 0 | 4 | 1 | 0 | 1 (2.3) | 1 (2.3) |
Serum creatinine level elevation | 0 | 6 | 0 | 0 | 0 (0) | 6 (14.3) |