Table 4 Genes and Functions in Ingenuity Pathways
From: Analysis of the interaction of extracellular matrix and phenotype of bladder cancer cells
Cluster/Network | Genes | Top Functions |
|---|---|---|
Matrigel_4/1 | AKT1, CLK2, CSE1L, DAPK1, FN1, G22P1, KRT7, KRT8, KRT18, PARP1, RAC1, TGFB1, TIMP2, TNFRSF1B, XRCC1, XRCC5 | DNA replication, Recombination and Repair; Cell Death; Neurological Disease |
Matrigel_4/2 | BAG1, CASP10, COPS5, CRADD, EIF2AK2, FASTIK, HNRPK, TP53BP1, TRAF6, XPO1 | Cell Cycle; Connective Tissue Disorders; Inflammatory Disease |
Plastic_7/1 | BIRC5, CTPS, DAP3, GADP, GLIPR1, HLA-DMA, MMP7, MMP11, MT3, RRM2, TIMP1, TXNRD1 | Cancer; Cell Death; Respiratory Disease |
Mat-Pla-SIS Common Genes/1 | AGC1, CASP8, CASP9, CDK2, DAPK1, FASTK, IL2, IL1A, KRT18, MAD2L1, MAPK6, MMP11, PDGFA, PHB, PMS2, STAT2, TIMP1, VNT | Cell Death; Cancer; Cell Cycle |
Mat-SIS Common Genes/1 | ADCYAP1R1, AKT1, CDC2, CDKN1A, CDKN1C, HLA-C, IL10, IL1B, ITGA7, KRT8, PDGFB, PMS1, SERPINB2, SPINT2, TGFB1 | Cancer; Cell Morphology; Cell Cycle |
Mat-SIS Common Genes/2 | CASP10, CBX5, CTNN1, DAB2, ELF1, G22P1, HNRPK, OAS1, RALB, TIMP2, XRCC5 | Cancer; Cell Death; Reproductive System Disease |