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Table 4 Genes and Functions in Ingenuity Pathways

From: Analysis of the interaction of extracellular matrix and phenotype of bladder cancer cells

Cluster/Network Genes Top Functions
Matrigel_4/1 AKT1, CLK2, CSE1L, DAPK1, FN1, G22P1, KRT7, KRT8, KRT18, PARP1, RAC1, TGFB1, TIMP2, TNFRSF1B, XRCC1, XRCC5 DNA replication, Recombination and Repair; Cell Death; Neurological Disease
Matrigel_4/2 BAG1, CASP10, COPS5, CRADD, EIF2AK2, FASTIK, HNRPK, TP53BP1, TRAF6, XPO1 Cell Cycle; Connective Tissue Disorders; Inflammatory Disease
Plastic_7/1 BIRC5, CTPS, DAP3, GADP, GLIPR1, HLA-DMA, MMP7, MMP11, MT3, RRM2, TIMP1, TXNRD1 Cancer; Cell Death; Respiratory Disease
Mat-Pla-SIS Common Genes/1 AGC1, CASP8, CASP9, CDK2, DAPK1, FASTK, IL2, IL1A, KRT18, MAD2L1, MAPK6, MMP11, PDGFA, PHB, PMS2, STAT2, TIMP1, VNT Cell Death; Cancer; Cell Cycle
Mat-SIS Common Genes/1 ADCYAP1R1, AKT1, CDC2, CDKN1A, CDKN1C, HLA-C, IL10, IL1B, ITGA7, KRT8, PDGFB, PMS1, SERPINB2, SPINT2, TGFB1 Cancer; Cell Morphology; Cell Cycle
Mat-SIS Common Genes/2 CASP10, CBX5, CTNN1, DAB2, ELF1, G22P1, HNRPK, OAS1, RALB, TIMP2, XRCC5 Cancer; Cell Death; Reproductive System Disease