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Table 2 Distribution of local relapses according to biologically effective radiation dose*

From: Prognostic factors in solitary plasmacytoma of the bone: a multicenter Rare Cancer Network study

All patients (n = 206) Tumors ≥ 5 cm (n = 59)
Radiation dose (Gy) Number of patients Local relapse (%) Number of patients Local relapse (%)
No RT** 5 4 (80%) 1 1 (100%)
<30 25 2 (8%) 2 0
≥ 30 – <40 55 5 (9%) 17 3 (18%)
≥ 40 – <50 65 8 (12%) 15 3 (20%)
≥ 50 56 8 (13%) 24 4 (17%)
  1. RT: radiation therapy
  2. *biologically effective dose (BED) according to the linear-quadratic model.13
  3. BED = nd(1+ [d÷α/β]) where n = number of fractions, d = dose per fraction, and α/β = 10 for plasmacytoma.
  4. **All patients treated with surgery alone (with chemotherapy in one).