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Table 3 treatment, delay to start of treatment and outcome of published cases

From: Plasmapheresis reverses all side-effects of a cisplatin overdose – a case report and treatment recommendation

age

sex

dosis

delay

treatment

outcome

author

41

f

200 mg/m2

4 hours

HD

alive, n.s.

Brivet et al.

36

m

480 mg/m2

6 days

HD

alive, CRF, hearing loss

Schiller et al.

62

m

240 mg/m2

3 days

STS, HD

alive, n.a.

Delanian et al.

68

f

280 mg/m2

12 days

PPH, HD

alive, CRF, hearing loss

Chu et al.

54

f

205 mg/m2

6 days

HD

alive, n.a.

Lagrange et al.

59

m

300 mg/m2

3 days

PPH

alive, n.s.

Jung et al.

38

f

total 640 mg

4 days

NAC

dead

Sheik-Hamad et al.

14

f

360 mg/m2

70 hours

STS

alive, hearing loss

Erdlenbruch et al.

48

m

400 mg/m2

no delay

PPH, HD

alive, n.s.

Choi et al.

63

m

total 750 mg

no delay

HD, NAC, PPH

dead

Charlier et al.

  1. HD: hemodialysis; STS: sodium thiosulfate; PPH: plasmapheresis; NAC: N-acetylcysteine; w.s.: with sequelae; n.s.: no sequelae; n.a.: not applicable; CRF: chronic renal failure