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Figure 3 | BMC Cancer

Figure 3

From: Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells

Figure 3

Effect of curcumin- and emodin-derived inhibitors on the stability of c-Jun and p53. Curcumin- and emodin-derived inhibitors of CSN-associated kinases affect the stability of c-Jun and p53 in HeLa or B8 cells. HeLa cells or B8 cells were incubated for 4 h with the inhibitors emodin, resveratrol, piceatannol, BTB14431 and JFD02836. The first lane is the control without inhibitor. Proteins of cell lysates were separated by SDS-PAGE and transferred to nitrocellulose. The Western blots analysis was probed with an anti-c-Jun or an anti-p53 antibody.

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