Table 1 Clinical data and results of conventional histology and immunohistology of adenomyoepithelial tumours of the breast.
Case | age | Diagnosis | Pleomorphism | Necrosis | Tumour border | CK14 | Ck19 | Ck18 | CD117 | Vim | P63 | Ck5/6 | S100 | KL-1 | SMA | MIB-1[%] | ER | PR | Mitoses/ 10HPF |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 42 | benign, biphasic AM/ tubular | 0 | 0 | s | (+++) | (++) | (++) | (++) | (+) | (+++) | (+++) | nd | (+) | (+++) | 2 | (+) | (+) | 0 |
2 | 57 | benign, biphasic AM/ tubular/ spindle-cellular | (+) | 0 | s | (+++) | (+++) | (+++) | 0 | (+) | nd | (+++) | nd | (+++) | (+++) | 5 | (+++) | (++) | 0 |
3 | 50 | benign, biphasic AM/ tubular/ lobular | (+) | (+) | s | (++) | (0) | (+) | (++) | (++) | (+++) | (+++) | nd | (+) | (+) | 10 | 0 | 0 | 1 |
4 | 75 | benign, biphasic AM/ lobular | (+) | 0 | s | (+) | (++) | (++) | (+) | (+) | (+++) | (++) | nd | (+) | (++) | 10 | (+) | 0 | 0 |
5 | 80 | Benign, biphasic AM/ lobular | (+) | (+) | i | (++) | (+) | (+) | (++) | nd | (+++) | (++) | (+) | (+) | (++) | 10 | 0 | 0 | 0 |
6 | 59 | benign, biphasic AM/ tubular/ spindle-cellular | (+) | 0 | s | nd | nd | nd | nd | (+) | nd | (+++) | nd | (++) | (+++) | 15 | (+++) | 0 | 1 |
7 | 65 | benign, monophasic AM/ spindle-cellular | (+) | 0 | s | (+++) | 0 | (+++) | 0 | (+++) | nd | (+++) | (+++) | (+++) | (+++) | 1 | 0 | 0 | 0 |
8 | 80 | benign, biphasic AM/ tubular/ spindle-cellular | (+) | 0 | s | (+++) | (+++) | (+++) | (+) | (+) | nd | (++) | (++) | (++) | (++) | 5 | 0 | 0 | 2 |
9 | 64 | borderline, monophasic AM/ spindle-cellular | (+) | 0 | i | (+++) | 0 | (+) | (+) | (+++) | (+++) | (+++) | nd | (+) | (+++) | 20 | 0 | 0 | 1 |
10 | 78 | borderline, monophasic AM/ spindle-cellular | (++) | (+) | i | nd | nd | nd | nd | nd | (+) | (+++) | (+) | (+) | (+) | 30 | 0 | 0 | 1 |
11 | 84 | borderline, monophasic AM/ spindle-cellular | (+++) | 0 | i | (+++) | 0 | (+) | (+) | (+++) | nd | (+++) | nd | (+) | (++) | 10 | 0 | 0 | 1 |
12 | 95 | borderline, monophasic AM/ spindle-cellular | (++) | 0 | i | nd | nd | nd | nd | nd | nd | (+++) | (+) | (+) | (+) | 20 | 0 | 0 | 1 |
13 | 66 | borderline, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | 0 | (+) | (++) | (+++) | (+++) | (+) | nd | 0 | (+) | 10 | 0 | 0 | 0 |
14 | 71 | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | 0 | (+) | (+) | (+++) | (+++) | (++) | nd | (+) | (+) | 20 | 0 | 0 | 1 |
15 | 68 | malignant, monophasic AM/ spindle-cellular | (++) | (+) | i | (+++) | (++) | (+) | (+) | (+++) | (+++) | (+++) | (+) | (+) | (++) | 40 | 0 | 0 | 12 |
16 | 93 | malignant Myoepithelioma | (+++) | (+) | i | (+) | 0 | 0 | (++) | (+++) | (+++) | (+++) | nd | (+) | (++) | 40 | 0 | 0 | 8 |
17 | 85 | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | 0 | (+) | (+) | (+++) | (+++) | (+++) | nd | (+) | (++) | 20 | 0 | 0 | 1 |
18 | 48 | malignant, monophasic AM/ spindle-cellular | (++) | 0 | i | nd | nd | nd | nd | nd | nd | (+++) | nd | (+) | (+++) | 25 | 0 | 0 | 6 |
19 | ? | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | (+) | (+) | 0 | (++) | (+++) | (+) | (+) | (+) | (+) | 50 | 0 | 0 | 25 |
20 | 81 | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | nd | nd | nd | nd | nd | nd | (+++) | (+) | (+) | (+) | 20 | 0 | 0 | 2 |
21 | 87 | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | 0 | (+) | 0 | (+++) | nd | (+++) | 0 | (++) | (+++) | 50 | 0 | 0 | 10 |
22 | 55 | malignant, monophasic AM/ spindle-cellular | (+++) | (+) | i | (+++) | (+++) | (++) | (+) | (+++) | nd | (+++) | (+) | (+) | (+) | 80 | 0 | 0 | 22 |
23 | 60 | malignant, biphasic AM/ spindle-cellular | (+++) | (+++) | i | (+++) | (+) | (+++) | (++) | (+++) | nd | (+++) | (+++) | (+++) | (+++) | 30 | 0 | 0 | 2 |
24 | 82 | malignant, monophasic AM/ spindle-cellular | (+++) | (+++) | i | (+++) | (++) | (++) | (++) | 0 | nd | (+) | (+) | (+) | (+++) | 75 | 0 | 0 | 12 |
25 | 57 | malignant, monophasic AM/ spindle-cellular | (++) | (++) | i | (+++) | (+) | (+) | (+) | (+) | nd | (++) | (+) | (+) | (++) | 70 | 0 | 0 | 62 |
26 | 45 | malignant, monophasic AM/ spindle-cellular | (+++) | (+++) | i | (+) | (+++) | (++) | (++) | (++) | nd | (++) | (+++) | (+) | (++) | 30 | 0 | 0 | 7 |
27 | 45 | malignant, monophasic AM/ spindle-cellular | (++) | (+++) | i | (+) | (+++) | (+++) | (++) | (++) | nd | (+) | (+) | (+++) | (++) | 60 | 0 | 0 | 11 |