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Table 3 Multivariate analysis of disease free survival in relation to the HIF-1α expression and other prognostic factors

From: HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor

Prognosticator

P valuea

RRb

Confidence intervalc

Tumor size

0.11

2.1

0.8–5.1

Nodal status

0.93

1.0

0.5–2,3

HIF-1α

0.01

0.3

0.1–0.7

Cyclin D1

0.43

1.4

0.6–3,0

Ki-67

0.99

1.0

0.6–1.8

  1. a The partially nonparametric regression model of Cox (1972) was used to evaluate the predictive power of vatious combinations of prognosticators in a multivariate manner.
  2. b RR, relative risk
  3. c 95% confidence interval