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Table 3 The sensitivities and specificities of the SELDI marker pattern, Cyfra21-1 and NSE.

From: Application of serum SELDI proteomic patterns in diagnosis of lung cancer

Items

Pattern

Cyfra21-1

NSE

Combination

Blinded test set

    

Sensitivity (%)

86.9 (73/84)

44.0(37/84)a

36.9(31/84)a

63.1(53/84)a

Specificity (%)

80.0 (24/30)

70.0(21/30)

73.3(22/30)

53.3(16/30) b

Whole set

    

Sensitivity (%)

 

46.2 (73/158)

35.4 (56/158)

62.0 (98/158)

Specificity (%)

 

72.0 (36/50)

74.0 (37/50)

56.0 (28/50)

  1. Pattern: SELDI marker pattern; Combination: combined use of Cyfra21-1 and NSE. a P < 0.005 compared with the SELDI marker pattern; b P < 0.05 compared with the SELDI marker pattern.