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Table 2 Radioiodide uptake in wild-type and transfected ARO cells

From: Recovery of NIS expression in thyroid cancer cells by overexpression of Pax8 gene

Cell type

Iodide uptake (cpm/well)

  

P

+ KClO4

P

ARO wild-type

133 ± 35

 

78 ± 26

**0.09

ARO pCMV

137 ± 42

*0.9

82 ± 47

**0.2

ARO-PAX8 clone 8

307 ± 43

*0.006

126 ± 27

**0.003

ARO-PAX8 clone 21

257 ± 36

*0.01

104 ± 26

**0.004

FRTL-5

4350 ± 320

   

CHO

40 ± 12

   
  1. Iodide uptake was analyzed as described in Methods. The FRTL-5 cells and CHO cells were used as positive and negative controls, respectively. Iodide uptake was expressed as the mean ± SD of values obtained from three separate experiments. Statistic analysis was performed using the one-factor ANOVA, followed by t test. P < 0.05 was considered statistically significant.
  2. * ARO PAX8 clone 8, clone 21 and ARO pCMV vs ARO wild-type;
  3. ** Uptake with vs Uptake without KClO4