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Table 2 Radioiodide uptake in wild-type and transfected ARO cells

From: Recovery of NIS expression in thyroid cancer cells by overexpression of Pax8 gene

Cell type Iodide uptake (cpm/well)
   P + KClO4 P
ARO wild-type 133 ± 35   78 ± 26 **0.09
ARO pCMV 137 ± 42 *0.9 82 ± 47 **0.2
ARO-PAX8 clone 8 307 ± 43 *0.006 126 ± 27 **0.003
ARO-PAX8 clone 21 257 ± 36 *0.01 104 ± 26 **0.004
FRTL-5 4350 ± 320    
CHO 40 ± 12    
  1. Iodide uptake was analyzed as described in Methods. The FRTL-5 cells and CHO cells were used as positive and negative controls, respectively. Iodide uptake was expressed as the mean ± SD of values obtained from three separate experiments. Statistic analysis was performed using the one-factor ANOVA, followed by t test. P < 0.05 was considered statistically significant.
  2. * ARO PAX8 clone 8, clone 21 and ARO pCMV vs ARO wild-type;
  3. ** Uptake with vs Uptake without KClO4