Figure 1From: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism MG-132 induces apoptosis in PC-3 cells. Representative (n = 3) FACS analysis of PC-3 prostate cancer cells incubated with 0, 25 and 50 μM concentrations of MG-132 for 24 h. TUNEL-staining indicated an increase of apoptotic cells from 7.6 % in control cells to 66.5 % and 72.8 % in MG-132 treated cells.Back to article page