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Table 2 Median LC90- (DiSC-assay) and Km-values (Casp3-test) for cytarabine, daunorubicin and mitoxantrone (range).

From: Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts

Drug LC90 (μg/ml) Km (μg/ml)
Cytarabine 1.40 (0.06 – 147.44) 0.270 (0.062 - >20)
Daunorubicin 0.63 (0.2 – 1.59) 0.443 (0.011 - >5)
Mitoxantrone 0.235 (0.02 – 3.34) 0.222 (0.007 - >20)