Figure 7From: Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity Representative images of Smad3 immunohistochemistry of controls (A, B) and XRT-WT vs. XRT-TG groups at 3 wk (C, D) and 14 wks (E, F). For Smad3, most positively stained cells are present in damaged areas of XRT-WT lungs, which showed significantly increased cell positivity when compared with XRT-TG animals. Representative images of p-Smad2/3 immunohistochemistry of XRT-WT vs. XRT-TG groups at 3 wk (G, H) and 14 wks (I, J) after irradiation. XRT-WT animals exhibited significantly increased positivity for p-Smad2/3 when compared with XRT-TG mice. See the results section for the details. Magnification × 400.Back to article page