Figure 5
From: Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity
Comparison of TGFβ1 activation in irradiated lung tissue. Increase active TGFβ1 expression began by 1 week. By 6 weeks, there was significantly more activated TGFβ1 in the lungs of XRT-WT mice (grey squares) vs. XRT-TG animals (grey triangles) (XRT-WT vs. XRT-TG, at 6, 10 and 14 wks, # p < 0.05). There were significantly more total TGFβ1 levels in XRT-WT (black squares) vs. XRT-TG animals (black triangles) at late time points (XRT-WT vs. XRT-TG, at 10 and 14 wks, * p < 0.05). Error bars represent 95% confidence intervals.