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Figure 2 | BMC Cancer

Figure 2

From: Preponderance of the oncogenic V599E and V599K mutations in B-raf kinase domain is enhanced in melanoma cutaneous/subcutaneous metastases

Figure 2

Part of the DNA sequence of the activation segment of the B-raf kinase domain. Representative melanoma resection specimens are shown which harbour missense mutations. In comparison to wild type DNA sequence (upper electropherogram, forward sequence on the left, reverse sequence on the right), melanoma cases 7, 23 and 54 exhibit nucleotide transitions, among them the activating T1796A mutation.

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BMC Cancer

ISSN: 1471-2407

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