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Table 2 Mutation analysis in 20 samples by SSCP and direct sequencing

From: Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from the Netherlands cohort study

   Direct sequencing
   Positive Negative
Primerset 3/4
SSCP Positive 0 5
  Negative 0 15
Primerset 5/6
SSCP Positive 2 0
  Negative 0 18
Primerset 7/8
SSCP Positive 4 2
  Negative 0 14
Primerset 9/10
SSCP Positive 3 0
  Negative 0 17
Primerset 11/12
SSCP Positive 4 1
  Negative 0 15
Primerset 13/14
SSCP Positive 2 0
  Negative 0 18
  1. Positive on SSCP means: indication of a mutation or not assessable after two attempts.
  2. Positive on direct sequencing means: proof of a mutation.