Figure 3

Overlayed SAM plots (for details, see Materials and Methods) from the donor v tumor, donor v adjacent normal and tumor v adjacent normal analyses. Each of the SAM plots was overlayed to direct comparison of the plots. The diagonal line represents no differential gene expression where the observed d value equals the expected d value after 1000 permutations of the class labels. Genes that are differentially expressed are displaced from the diagonal (greater than 0 for up regulation and less than 0 for down regulation). Genes that are more differentially expressed are more displaced from the diagonal than those that are closer to the diagonal. For each of the comparisons, a plot is generated from the d values of the 12625 probe sets in the two specimen groups. Red = donor v tumor plot; green = adjacent normal v tumor plot; black = adjacent normal v donor plot.