Figure 2

Regression analysis of permuted donors, adjacent normal and tumor samples. The 60 tumors and 63 adjacent normal tissues were segmented so that tumors and adjacent normal samples in each comparison were selected from different patients. The resulting tumor and adjacent normal samples were then subjected to regression analysis. Donor v tumor, donor v adjacent normal and adjacent normal comparisons were performed. Since the segmentation can be performed in many different ways, the analysis was performed 1000 times. The mean correlation coeifficient and standard deviation from each of these comparisons were plotted as box plots.