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Table 5 Methylation and gene re-expression of the 12 informative cases.

From: A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

   Pre-treat Post-treat Re-expression
Gene dose level M U M U Yes/No
DAPK 50 + - + - No
DAPK 50 + - + - No
GSTp1 50 + - + - No
FHIT 100 + - + + Yes
FHIT 150 + - + + Yes
MGMT 75 + - + + Yes
MGMT 150 + - + + Yes
GSTp1 50 + - + + Yes
DAPK 75 + - - + Yes
ER 75 + - - + Yes
GSTp1 150 + - - + Yes
GSTp1 75 + + - + Yes