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Table 4 Toxicity to hydralazine expressed by number of patients suffering the event (16 patients)

From: A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

Toxicity 4 Patients in each dose level (mg
  50 75 100 150
Nausea 2/4 - 2/4* 2/2
Vomiting - - - -
Dizziness - 1/4* 1/4 -
Fatigue 2/4 2/4 3/4 1/4
Flushes - - - -
Headache 2/4 1/4 3/4 2/4
Edema - - - -
Palpitations 1/4 2/4 2/4 3/4
  1. * Grade 2 toxicity. All other were grade 1.