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Table 4 Toxicity to hydralazine expressed by number of patients suffering the event (16 patients)

From: A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

Toxicity

4 Patients in each dose level (mg

 

50

75

100

150

Nausea

2/4

-

2/4*

2/2

Vomiting

-

-

-

-

Dizziness

-

1/4*

1/4

-

Fatigue

2/4

2/4

3/4

1/4

Flushes

-

-

-

-

Headache

2/4

1/4

3/4

2/4

Edema

-

-

-

-

Palpitations

1/4

2/4

2/4

3/4

  1. * Grade 2 toxicity. All other were grade 1.
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BMC Cancer

ISSN: 1471-2407

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