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Table 3 Univariate and multivariate analysis for pretreatment IL-6 serum levels (Group B)

From: The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy

  Local control Regional control Disease-free survival Overall survival
  RR 95% CI P value RR 95% CI P value RR 95% CI P value RR 95% CI P value
Univariate 0.98 1.39–9.78 0.03 1.29 0.37–4.53 0.68 3.24 1.25–8.50 0.05 8.30 2.44–28.50 0.0009
Multivariate 4.06 1.40–11.70 0.009 1.80 0.40–8.17 0.45 3.39 1.22–9.39 0.02 7.61 1.82–31.80 0.005
  1. Univariate and multivariate analysis (Cox proportional hazard model) for IL-6 (> or < median) towards local control, regional control, disease-free survival and overall survival. Significant P values are marked in bold. RR: relative risk. CI: confidence interval.