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Table 3 Univariate and multivariate analysis for pretreatment IL-6 serum levels (Group B)

From: The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy

 

Local control

Regional control

Disease-free survival

Overall survival

 

RR

95% CI

P value

RR

95% CI

P value

RR

95% CI

P value

RR

95% CI

P value

Univariate

0.98

1.39–9.78

0.03

1.29

0.37–4.53

0.68

3.24

1.25–8.50

0.05

8.30

2.44–28.50

0.0009

Multivariate

4.06

1.40–11.70

0.009

1.80

0.40–8.17

0.45

3.39

1.22–9.39

0.02

7.61

1.82–31.80

0.005

  1. Univariate and multivariate analysis (Cox proportional hazard model) for IL-6 (> or < median) towards local control, regional control, disease-free survival and overall survival. Significant P values are marked in bold. RR: relative risk. CI: confidence interval.