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Table 2 Multivariate analysis for Group A

From: The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy

 

Local Control

Regional Control

Disease-free Survival

Overall Survival

Parameter

   RR   

95% CI

P value

   RR   

95% CI

P value

   RR   

95% CI

P value

   RR   

95% CI

P value

T1-2 vs. T3-4

1.21

0.58–2.53

0.62

2.74

0.99–7.62

0.05

1.40

0.70–2.83

0.34

3.85

1.46–10.18

0.006

N 0-1-2 vs. N3

3.75

1.47–9.60

0.006

7.68

2.72–21.70

0.0001

5.70

2.34–13.85

0.0001

6.05

2.32–15.77

0.0002

Differentiation

1.50

0.90–2.49

0.12

1.64

0.89–3.02

0.11

1.49

0.93–2.40

0.12

0.81

0.45–1.47

0.49

Perfusion > median

0.55

0.28–1.09

0.09

1.07

0.46–2.51

0.87

0.61

0.32–1.15

0.12

0.65

0.48–0.88

0.28

GLUT-1 & CA IX > median

2.33

1.12–4.82

0.02

2.24

0.97–11.58

0.06

2.06

1.05–4.07

0.04

1.53

0.65–3.60

0.33

  1. Multivariate analysis (Cox proportional hazard model) for Group A towards local control, regional control, disease-free survival and overall survival. Significant P values are marked in bold. RR: relative risk. CI: confidence interval.