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Table 4 Summary of toxicity by age, radiotherapy and combined subgroups expressed as row percentages)

From: Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience

 

Haematologic

Other

Any

Subgroup

G0-2

G3-4

p*

G0-2

G3-4

p*

G0-2

G3-4

p*

Age

  

0.17

  

0.49

  

1.00

>60 and <65 years (n = 100)

86%

14%

 

72%

28%

 

62%

38%

 

≥ 65 years (n = 80)

78%

22%

 

78%

22%

 

61%

39%

 

Radiotherapy

  

<0.0001

  

0.21

  

0.27

No (n = 114)

92%

8%

 

71%

29%

 

65%

35%

 

Yes (n = 66)

65%

35%

 

80%

20%

 

56%

44%

 

Age and radiotherapy

  

<0.0001

  

0.42

  

0.08

>60 and < 65, no RT (n = 64)

92%

8%

 

67%

33%

 

59%

41%

 

≥ 65, no RT (n = 50)

92%

8%

 

76%

24%

 

72%

28%

 

>60 and < 65, RT (n = 36)

75%

25%

 

81%

19%

 

67%

33%

 

≥ 65, RT (n = 30)

53%

47%

 

80%

20%

 

43%

57%

 
  1. G = grade; RT = radiotherapy.