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Table 2 Worst degree of toxicity by age group (% of patients)

From: Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience

Type of toxicity

>60 and <65 years (n = 100)

≥ 65 years (n = 80)

P*

 

0

1

2

3

4

0

1

2

3

4

 

Anemia

81

10

8

0

1

86

6

4

4

0

0.39

Leukopenia

54

15

19

7

5

45

11

26

11

6

0.13

Neutropenia

73

10

8

5

4

68

9

7

10

6

0.32

Febrile Neutropenia

100

-

-

0

0

96

-

-

4

0

0.05

Infection

97

0

1

2

0

95

0

2.5

2.5

0

0.50

Fever

98

0

2

0

0

98

2

0

0

0

0.83

Thrombocytopenia

90

7

2

0

1

91

4

1

3

1

0.83

Bleeding

98

1

0

1

0

100

0

0

0

0

0.21

Nausea

81

8

6

5

0

69

11

12

8

0

0.06

Vomiting

71

5

11

13

0

69

9

16

6

0

0.98

Mucositis

84

5

8

3

0

92

1

5

1

0

0.09

Skin

99

1

0

0

0

98

0

2

0

0

0.43

Diarrhea

96

1

0

3

0

96

3

1

0

0

0.91

Constipation

99

0

0

1

0

98

1

1

0

0

0.45

Hepatic

88

3

7

2

0

90

6

4

0

0

0.60

Cardiac

100

0

0

0

0

96

0

2.5

1

0

0.09

Fatigue

96

1

3

0

0

95

0

2.5

2.5

0

0.72

Pulmonary

100

0

0

0

0

99

1

0

0

0

0.27

Abdominal pain

99

0

0

1

0

99

0

0

1

0

0.88

Chest pain

99

0

0

1

0

100

0

0

0

0

0.37

Heartburn

99

0

1

0

0

98

0

2

0

0

0.44

Headache

99

0

0

1

0

100

0

0

0

0

0.38

Confusion

99

1

0

0

0

100

0

0

0

0

0.38

Depression

100

0

0

0

0

99

0

0

1

0

0.27

Thrombophlebitis

97

0

0

3

0

94

0

0

6

0

0.30

Dysuria

99

0

0

1

0

99

0

0

1

0

0.88

Allergy

99

0

0

1

0

100

0

0

0

0

0.37

Weight gain

100

0

0

0

0

99

0

1

0

0

0.27

Weight loss

99

0

1

0

0

99

1

0

0

0

0.89

  1. * Wilcoxon-Mann Whitney test