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Table 2 Worst degree of toxicity by age group (% of patients)

From: Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience

Type of toxicity >60 and <65 years (n = 100) ≥ 65 years (n = 80) P*
  0 1 2 3 4 0 1 2 3 4  
Anemia 81 10 8 0 1 86 6 4 4 0 0.39
Leukopenia 54 15 19 7 5 45 11 26 11 6 0.13
Neutropenia 73 10 8 5 4 68 9 7 10 6 0.32
Febrile Neutropenia 100 - - 0 0 96 - - 4 0 0.05
Infection 97 0 1 2 0 95 0 2.5 2.5 0 0.50
Fever 98 0 2 0 0 98 2 0 0 0 0.83
Thrombocytopenia 90 7 2 0 1 91 4 1 3 1 0.83
Bleeding 98 1 0 1 0 100 0 0 0 0 0.21
Nausea 81 8 6 5 0 69 11 12 8 0 0.06
Vomiting 71 5 11 13 0 69 9 16 6 0 0.98
Mucositis 84 5 8 3 0 92 1 5 1 0 0.09
Skin 99 1 0 0 0 98 0 2 0 0 0.43
Diarrhea 96 1 0 3 0 96 3 1 0 0 0.91
Constipation 99 0 0 1 0 98 1 1 0 0 0.45
Hepatic 88 3 7 2 0 90 6 4 0 0 0.60
Cardiac 100 0 0 0 0 96 0 2.5 1 0 0.09
Fatigue 96 1 3 0 0 95 0 2.5 2.5 0 0.72
Pulmonary 100 0 0 0 0 99 1 0 0 0 0.27
Abdominal pain 99 0 0 1 0 99 0 0 1 0 0.88
Chest pain 99 0 0 1 0 100 0 0 0 0 0.37
Heartburn 99 0 1 0 0 98 0 2 0 0 0.44
Headache 99 0 0 1 0 100 0 0 0 0 0.38
Confusion 99 1 0 0 0 100 0 0 0 0 0.38
Depression 100 0 0 0 0 99 0 0 1 0 0.27
Thrombophlebitis 97 0 0 3 0 94 0 0 6 0 0.30
Dysuria 99 0 0 1 0 99 0 0 1 0 0.88
Allergy 99 0 0 1 0 100 0 0 0 0 0.37
Weight gain 100 0 0 0 0 99 0 1 0 0 0.27
Weight loss 99 0 1 0 0 99 1 0 0 0 0.89
  1. * Wilcoxon-Mann Whitney test
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