Type of toxicity | >60 and <65 years (n = 100) | ≥ 65 years (n = 80) | P* | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 | 0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 |  |
Anemia | 81 | 10 | 8 | 0 | 1 | 86 | 6 | 4 | 4 | 0 | 0.39 |
Leukopenia | 54 | 15 | 19 | 7 | 5 | 45 | 11 | 26 | 11 | 6 | 0.13 |
Neutropenia | 73 | 10 | 8 | 5 | 4 | 68 | 9 | 7 | 10 | 6 | 0.32 |
Febrile Neutropenia | 100 | - | - | 0 | 0 | 96 | - | - | 4 | 0 | 0.05 |
Infection | 97 | 0 | 1 | 2 | 0 | 95 | 0 | 2.5 | 2.5 | 0 | 0.50 |
Fever | 98 | 0 | 2 | 0 | 0 | 98 | 2 | 0 | 0 | 0 | 0.83 |
Thrombocytopenia | 90 | 7 | 2 | 0 | 1 | 91 | 4 | 1 | 3 | 1 | 0.83 |
Bleeding | 98 | 1 | 0 | 1 | 0 | 100 | 0 | 0 | 0 | 0 | 0.21 |
Nausea | 81 | 8 | 6 | 5 | 0 | 69 | 11 | 12 | 8 | 0 | 0.06 |
Vomiting | 71 | 5 | 11 | 13 | 0 | 69 | 9 | 16 | 6 | 0 | 0.98 |
Mucositis | 84 | 5 | 8 | 3 | 0 | 92 | 1 | 5 | 1 | 0 | 0.09 |
Skin | 99 | 1 | 0 | 0 | 0 | 98 | 0 | 2 | 0 | 0 | 0.43 |
Diarrhea | 96 | 1 | 0 | 3 | 0 | 96 | 3 | 1 | 0 | 0 | 0.91 |
Constipation | 99 | 0 | 0 | 1 | 0 | 98 | 1 | 1 | 0 | 0 | 0.45 |
Hepatic | 88 | 3 | 7 | 2 | 0 | 90 | 6 | 4 | 0 | 0 | 0.60 |
Cardiac | 100 | 0 | 0 | 0 | 0 | 96 | 0 | 2.5 | 1 | 0 | 0.09 |
Fatigue | 96 | 1 | 3 | 0 | 0 | 95 | 0 | 2.5 | 2.5 | 0 | 0.72 |
Pulmonary | 100 | 0 | 0 | 0 | 0 | 99 | 1 | 0 | 0 | 0 | 0.27 |
Abdominal pain | 99 | 0 | 0 | 1 | 0 | 99 | 0 | 0 | 1 | 0 | 0.88 |
Chest pain | 99 | 0 | 0 | 1 | 0 | 100 | 0 | 0 | 0 | 0 | 0.37 |
Heartburn | 99 | 0 | 1 | 0 | 0 | 98 | 0 | 2 | 0 | 0 | 0.44 |
Headache | 99 | 0 | 0 | 1 | 0 | 100 | 0 | 0 | 0 | 0 | 0.38 |
Confusion | 99 | 1 | 0 | 0 | 0 | 100 | 0 | 0 | 0 | 0 | 0.38 |
Depression | 100 | 0 | 0 | 0 | 0 | 99 | 0 | 0 | 1 | 0 | 0.27 |
Thrombophlebitis | 97 | 0 | 0 | 3 | 0 | 94 | 0 | 0 | 6 | 0 | 0.30 |
Dysuria | 99 | 0 | 0 | 1 | 0 | 99 | 0 | 0 | 1 | 0 | 0.88 |
Allergy | 99 | 0 | 0 | 1 | 0 | 100 | 0 | 0 | 0 | 0 | 0.37 |
Weight gain | 100 | 0 | 0 | 0 | 0 | 99 | 0 | 1 | 0 | 0 | 0.27 |
Weight loss | 99 | 0 | 1 | 0 | 0 | 99 | 1 | 0 | 0 | 0 | 0.89 |