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Table 3 Distribution of baseline demographic, socioeconomic, and clinical characteristics by screening status.

From: Differences between men with screening-detected versus clinically diagnosed prostate cancers in the USA

Variable

Clinically diagnosed (weighted %)

Asymptomatic* (weighted %)

LUTS** (weighted %)

Asymptomatic or LUTS*** (weighted %)

SEER registry

 

P = 0.16*

P = 0.31**

P = 0.24***

   Atlanta

14.2

14.2

12.9

13.3

   Connecticut

19.1

24.7

21.9

22.9

   Los Angeles

38.1

34.5

36.0

35.5

   New Mexico

13.7

9.8

12.0

11.3

   Seattle

4.3

5.9

6.4

6.2

   Utah

10.5

10.9

10.8

6.8

Ethnicity

 

P < 0.01

P < 0.01

P < 0.01

   Non-Hispanic white

65.1

79.9

75.5

77.0

   Non-Hispanic black

20.8

12.4

13.3

13.0

   Hispanic

14.1

7.8

11.2

10.0

Age

 

P < 0.01

P = 0.38

P ≤ 0.01

   < 49

2.2

4.1

1.4

2.3

   50–64

22.8

40.5

29.7

33.4

   65–74

50.7

38.7

46.5

43.8

   75+

24.4

16.7

22.4

20.5

Current marital status

 

P < 0.01

P = 0.03

P = 0.01

   Married

72.9

81.4

79.7

80.3

   Unmarried

27.1

18.6

20.3

19.7

Education

 

P < 0.01

P < 0.01

P < 0.01

   < High school degree

33.3

16.2

21.7

19.8

   High school/college

37.6

45.5

44.8

45.0

   ≥ College degree

29.7

38.3

33.5

35.2

Income (annual)

 

P < 0.01

P = 0.01

P < 0.01

   < $20,000

36.8

19.0

28.4

25.1

   $20 – 40,000

35.9

30.3

33.2

32.2

   $40,000 +

27.3

50.7

38.4

42.7

Insurance

 

P < 0.01

P = 0.23

P = 0.01

   Private

39.7

48.9

44.0

44.3

   Public/Medicare

53.1

42.7

48.2

48.2

   Unknown

6.4

8.4

7.9

8.1

Comorbid conditions

 

P ≤ 0.01

P = 0.41

P = 0.05

   None

32.2

41.8

35.8

37.8

   1

30.3

34.0

32.2

32.8

   2

17.6

16.4

16.1

16.2

   3+

19.8

7.8

16.0

13.2

Health status

 

P < 0.01

P < 0.01

P < 0.01

   Excellent

9.9

23.0

15.2

17.9

   Good

63.5

68.9

66.5

67.3

   Fair or poor

26.6

8.1

18.3

14.8

PSA (ng/ml)

 

P = 0.01

P = 0.20

P = 0.05

   <4

11.7

7.0

9.3

8.5

   ≥ 4

78.5

87.9

83.7

85.2

   Unknown

9.8

5.1

7.0

6.4

Digital rectal examination

 

P = 0.10

P = 0.07

P = 0.06

   Abnormal

59.4

54.0

54.3

54.2

   Normal

27.0

34.0

33.9

33.9

   Unknown

13.6

12.0

11.7

11.9

Gleason score

 

P < 0.01

P < 0.01

P < 0.01

   2 – 4

9.6

13.6

14.9

14.4

   5 – 7

53.4

69.9

64.6

66.5

   8 – 10

22.3

8.3

11.4

10.3

   Unknown

14.7

8.2

9.1

8.8

Tumor stage

 

P < 0.01

P < 0.01

P < 0.01

   Local

74.6

92.8

89.1

90.4

   Regional

4.0

3.2

4.0

3.7

   Advanced

21.4

4.0

7.0

5.9

  1. *P value comparing asymptomatic cases with clinically diagnosed cases.
  2. ** P value comparing lower urinary tract symptoms alone cases with clinically diagnosed cases.
  3. ***P value comparing asymptomatic and lower urinary tract symptoms alone cases with clinically diagnosed cases.
  4. Legend: LUTS = lower urinary tract symptoms, SEER = Surveillance, Epidemiology, and End Results; PSA = prostate-specific antigen