Variable
|
Clinically diagnosed (weighted %)
|
Asymptomatic* (weighted %)
|
LUTS** (weighted %)
|
Asymptomatic or LUTS*** (weighted %)
|
---|
SEER registry
| |
P = 0.16*
|
P = 0.31**
|
P = 0.24***
|
Atlanta
|
14.2
|
14.2
|
12.9
|
13.3
|
Connecticut
|
19.1
|
24.7
|
21.9
|
22.9
|
Los Angeles
|
38.1
|
34.5
|
36.0
|
35.5
|
New Mexico
|
13.7
|
9.8
|
12.0
|
11.3
|
Seattle
|
4.3
|
5.9
|
6.4
|
6.2
|
Utah
|
10.5
|
10.9
|
10.8
|
6.8
|
Ethnicity
| |
P < 0.01
|
P < 0.01
|
P < 0.01
|
Non-Hispanic white
|
65.1
|
79.9
|
75.5
|
77.0
|
Non-Hispanic black
|
20.8
|
12.4
|
13.3
|
13.0
|
Hispanic
|
14.1
|
7.8
|
11.2
|
10.0
|
Age
| |
P < 0.01
|
P = 0.38
|
P ≤ 0.01
|
< 49
|
2.2
|
4.1
|
1.4
|
2.3
|
50–64
|
22.8
|
40.5
|
29.7
|
33.4
|
65–74
|
50.7
|
38.7
|
46.5
|
43.8
|
75+
|
24.4
|
16.7
|
22.4
|
20.5
|
Current marital status
| |
P < 0.01
|
P = 0.03
|
P = 0.01
|
Married
|
72.9
|
81.4
|
79.7
|
80.3
|
Unmarried
|
27.1
|
18.6
|
20.3
|
19.7
|
Education
| |
P < 0.01
|
P < 0.01
|
P < 0.01
|
< High school degree
|
33.3
|
16.2
|
21.7
|
19.8
|
High school/college
|
37.6
|
45.5
|
44.8
|
45.0
|
≥ College degree
|
29.7
|
38.3
|
33.5
|
35.2
|
Income (annual)
| |
P < 0.01
|
P = 0.01
|
P < 0.01
|
< $20,000
|
36.8
|
19.0
|
28.4
|
25.1
|
$20 – 40,000
|
35.9
|
30.3
|
33.2
|
32.2
|
$40,000 +
|
27.3
|
50.7
|
38.4
|
42.7
|
Insurance
| |
P < 0.01
|
P = 0.23
|
P = 0.01
|
Private
|
39.7
|
48.9
|
44.0
|
44.3
|
Public/Medicare
|
53.1
|
42.7
|
48.2
|
48.2
|
Unknown
|
6.4
|
8.4
|
7.9
|
8.1
|
Comorbid conditions
| |
P ≤ 0.01
|
P = 0.41
|
P = 0.05
|
None
|
32.2
|
41.8
|
35.8
|
37.8
|
1
|
30.3
|
34.0
|
32.2
|
32.8
|
2
|
17.6
|
16.4
|
16.1
|
16.2
|
3+
|
19.8
|
7.8
|
16.0
|
13.2
|
Health status
| |
P < 0.01
|
P < 0.01
|
P < 0.01
|
Excellent
|
9.9
|
23.0
|
15.2
|
17.9
|
Good
|
63.5
|
68.9
|
66.5
|
67.3
|
Fair or poor
|
26.6
|
8.1
|
18.3
|
14.8
|
PSA (ng/ml)
| |
P = 0.01
|
P = 0.20
|
P = 0.05
|
<4
|
11.7
|
7.0
|
9.3
|
8.5
|
≥ 4
|
78.5
|
87.9
|
83.7
|
85.2
|
Unknown
|
9.8
|
5.1
|
7.0
|
6.4
|
Digital rectal examination
| |
P = 0.10
|
P = 0.07
|
P = 0.06
|
Abnormal
|
59.4
|
54.0
|
54.3
|
54.2
|
Normal
|
27.0
|
34.0
|
33.9
|
33.9
|
Unknown
|
13.6
|
12.0
|
11.7
|
11.9
|
Gleason score
| |
P < 0.01
|
P < 0.01
|
P < 0.01
|
2 – 4
|
9.6
|
13.6
|
14.9
|
14.4
|
5 – 7
|
53.4
|
69.9
|
64.6
|
66.5
|
8 – 10
|
22.3
|
8.3
|
11.4
|
10.3
|
Unknown
|
14.7
|
8.2
|
9.1
|
8.8
|
Tumor stage
| |
P < 0.01
|
P < 0.01
|
P < 0.01
|
Local
|
74.6
|
92.8
|
89.1
|
90.4
|
Regional
|
4.0
|
3.2
|
4.0
|
3.7
|
Advanced
|
21.4
|
4.0
|
7.0
|
5.9
|
- *P value comparing asymptomatic cases with clinically diagnosed cases.
- ** P value comparing lower urinary tract symptoms alone cases with clinically diagnosed cases.
- ***P value comparing asymptomatic and lower urinary tract symptoms alone cases with clinically diagnosed cases.
- Legend: LUTS = lower urinary tract symptoms, SEER = Surveillance, Epidemiology, and End Results; PSA = prostate-specific antigen