Low frequency of defective mismatch repair in a population-based series of upper urothelial carcinoma

BMC Cancer

Table 1 Clinicopathological data of MMR-defective tumors

Case no.	Sex / Age	Tumor location (Synchron./Metachron.)	WHO-Grade	Stage	Instable markers	Immunohistochemical expression
						MLH1	MSH2	MSH6	PMS2
U1-113	F/54	ureter	G2	pTX	NE	+	-	-	+
	53	endometrium (M)			4/6	+	-	-	+
U2-229	F/57	ureter	G2	pT1	4–5/6	-	+	+	-
	57	ureter (S)			4–5/6	-	+	+	-
U3-821	M/61	ureter*	G2	pT1	2–3/6	+	-	-	+
RP1-101	M/60	renal pelvis	G2	pT3	3/5	+	-	-	+
	43	sarcoma (M)			3/4	+	-	-	+
	53	colon (M)			1/6¤	+	-	-	+
RP2-131	M/75	renal pelvis	G3	pT4	2/6	+	+	+	+
RP3-119	F/69	renal pelvis	G3	pTa	0/6	-	+	NE	-
RP4-267	F/67	renal pelvis	G2	pT1	5/5	+	-	-	+
	70	urinary bladder (M)			3/4	+	-	-	+
RP5-401	M/56	renal pelvis	G2	pTa	0/6	+	+	-	+
RP6-528	F/87	renal pelvis	G2	pT1	2/5	+	+	+	+
	87	urinary bladder (S)			0/6	+	+	+	+
RP7-613	F/57	renal pelvis^	G2	pT1	3/6	+	+	-	+
	54	urinary bladder (M)			4/6	+	-	-	+
RP8-626	M/66	renal pelvis	G3	pT2	6/6	+	-	-	+
RP9-701	F/49	renal pelvis#	G2	pTa	0/5	+	-	NE	+
RP10-809	F/82	renal pelvis	G3	pT4	4/4	+	-	-	+

ISSN: 1471-2407