Figure 3

Effect of doxorubicin on c-FLIP in vivoMice bearing PC3 xenografts were untreated or treated with 4 mg/kg or 8 mg/kg doxorubicin (i.p.). After 24 hours, protein was isolated from xenografts (A) or mouse heart (B) and probed for c-FLIP expression by western blotting. Actin was included as a loading control.