Skip to main content

Table 4 Clinico-pathologic and immunohistochemical parameters in relation to Mcm2 immunoreactivity

From: Expression of minichromosome maintenance protein 2 as a marker for proliferation and prognosis in diffuse large B-cell lymphoma: a tissue microarray and clinico-pathological analysis

   Mcm2 immunoreactivity
Variable Categorisation n analysable negative (<40%) positive (≥40%) pa
Clinico-pathologic data:
Age at diagnosis
  <65 years 47 27 20 1.000
  ≥65 years 63 37 26  
Gender
  male 72 39 33 0.593
  female 57 34 23  
Ann Arbor Stage
  1 15 10 5 0.342
  2 34 15 19  
  3 23 14 9  
  4 35 22 13  
International prognostic index
  0 2 2 0 0.122
  1 48 27 21  
  2 21 14 7  
  3 20 13 7  
  4 14 4 10  
Bone marrow involvement
  no 72 39 33 0.414
  yes 35 22 13  
Extranodal involvement
  no 40 27 13 0.103
  yes 62 31 31  
Bulky disease
  no 62 44 20 0.003
  yes 35 13 22  
Serum levels of LDH at diagnosis
  <300 U/l 42 23 19 0.505
  ≥300 U/l 41 26 15  
  1. a two-sided Fisher's exact test; bold type representing significant data.