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Table 2 Performance of metric variables in prediction of mortality using the AUROC (area under the receiver operating characteristic curve) method

From: Expression of minichromosome maintenance protein 2 as a marker for proliferation and prognosis in diffuse large B-cell lymphoma: a tissue microarray and clinico-pathological analysis

 

Mcm2 IHCc

LDHd

Optimum cutoff value

39.5%

306 U/l

Sensitivityb

0.512

0.620

Specificityb

0.696

0.476

AUROCa

0.582

0.553

95% confidence interval

0.462–0.702

0.434–0.672

p (asymtptotic significance)

0.182

0.384

  1. a AUROC, area under the receiver operating characteristic curve.
  2. b sensitivity and specificity were calculated for the cutoff, which represented the best discrimination as derived from the ROC curves.
  3. c IHC: immunohistochemistry
  4. d LDH: lactate dehydrogenase