Table 2 Effects of various cDNA constructs on cell growth after transfection into neuroblastoma and other tumour cell lines.
From: Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death
Cell Line | Gene | day | % decrease in number of cells +/-SD | number of experiments | p-value: test |
|---|---|---|---|---|---|
SK-N-AS | Empty vector (control) | - | 3 × 8 | ||
ENO1 | 1 | 22 +/- 8 | 3 × 8 | < 0.001 | |
2 | 21 +/- 4 | 3 × 8 | 0.004 | ||
3 | 13 +/- 3 | 3 × 8 | 0.04 | ||
4 | 27 +/- 12 | 3 × 8 | < 10 -5 | ||
CORT | 1 | 3 +/- 7 | 1 × 8 | > 0.05 | |
2 | -10 +/- 14 | 1 × 8 | > 0.05 | ||
3 | 18 +/- 14 | 1 × 8 | 0.004 | ||
4 | 4 +/- 8 | 1 × 8 | > 0.05 | ||
DFFA | 1 | 2 +/- 8 | 1 × 8 | > 0.05 | |
2 | 6 +/- 11 | 1 × 8 | > 0.05 | ||
3 | 19 +/- 12 | 1 × 8 | 0.002 | ||
4 | 14 +/- 6 | 1 × 8 | < 10 -6 | ||
ICAT | 1 | -6 +/- 10 | 1 × 8 | 0.04 | |
2 | -3 +/- 9 | 1 × 8 | > 0.05 | ||
3 | 0 +/- 23 | 1 × 8 | > 0.05 | ||
4 | -2 +/- 6 | 1 × 8 | > 0.05 | ||
PEX14 | 1 | 1 +/- 10 | 1 × 8 | > 0.05 | |
2 | -9 +/- 18 | 1 × 8 | > 0.05 | ||
3 | 15 +/- 18 | 1 × 8 | 0.02 | ||
4 | 9 +/- 7 | 1 × 8 | 0.001 | ||
PGD | 1 | 12 +/- 8 | 1 × 8 | < 0.001 | |
2 | -1 +/- 16 | 1 × 8 | > 0.05 | ||
3 | 24 +/- 15 | 1 × 8 | < 0.001 | ||
4 | 11 +/- 7 | 1 × 8 | < 10 -4 | ||
IMR32 | ENO1 | 1 | 12 +/- 16 | 1 × 8 | 0.02 |
2 | 23 +/- 14 | 1 × 8 | 0.01 | ||
3 | 14 +/- 14 | 1 × 8 | < 0.001 | ||
4 | 18 +/- 8 | 1 × 8 | < 10 -5 | ||
293 | ENO1 | 1 | 15 +/- 20 | 1 × 8 | 0.03 |
2 | 49 +/- 29 | 1 × 8 | 0.006 | ||
3 | 19 +/- 10 | 1 × 8 | < 0.001 | ||
4 | 46 +/- 9 | 1 × 8 | < 10 -7 |