Figure 1

Distribution of aberrations in the APC and K-ras genes and hMLH1 expression in 656 colorectal tumours. The data in this figure are based on tumours from 656 sporadic colorectal cancer patients. The bars representing the different molecular alterations represent mutually exclusive groups of tumours. The category "Other" includes; APC silent mutation (n = 25), K-ras mutations other than missense mutations in codons 12 and 13 (n = 2), and both of these (n = 1).