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Figure 2 | BMC Cancer

Figure 2

From: Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies

Figure 2

Frequency plots of predominant IHC score for phospho-Akt and cIAP-2/BIRC3 in human pre-neoplastic bronchial biopsies. Pre-neoplastic biopsies were scored based on the predominant staining intensity observed using a scale of 0 for negative, 1 for faint, 2 for moderate and 3 for strong. Each symbol represents a separate biopsy and the horizontal line represents the mean score for each category: normal, hyperplasia, mild or moderate dysplasia, severe dysplasia or carcinoma in situ and carcinoma. (A), Scores for predominant phospho-Akt staining intensity. Mean scores were: normal, 1.0; hyperplasia, 1.3; mild or moderate dysplasia, 2.0; severe dysplasia or carcinoma in situ, 2.6; carcinoma, 1.6. (B), Scores for predominant cIAP-2/BIRC3 staining intensity. Mean scores were: normal, 1.1; hyperplasia, 0.89; mild or moderate dysplasia, 0.86; severe dysplasia or carcinoma in situ, 1.8; carcinoma, 1.8.

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