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Table 4 Risk of cancer for relatives of lung cancer probands and controls

From: Increased risk of cancer among relatives of patients with lung cancer in China

Relatives

Lung cancer ORb (95% CI)

Non-lung cancer ORb (95% CI)

Any cancer ORb (95% CI)

All relativesa

2.05(1.68–2.53)**

1.41(1.08–2.13)*

1.82(1.52–2.02)**

Female relatives

2.17(1.60–3.64)**

2.00(1.26–3.01)**

2.45(1.84–3.20)**

Male relatives

1.33(1.02–2.02)*

1.03(0.78–1.62)

1.36(1.05–1.68)*

Parents

2.90(1.97–4.32)**

1.52(1.01–2.30)*

2.16(1.62–2.87)**

Fathers

2.17 (1.21–3.86)*

1.30(0.86–2.27)

1.80(1.20–2.69)**

Mothers

2.78(1.23–5.12)**

2.34(1.28–4.40)**

3.12(2.03–4.66)**

Siblings

1.65(1.19–2.18)*

1.31(0.97–2.01)*

1.51(1.28–1.80)**

Brothers

1.21(0.79–1.80)

0.92(0.72–1.68)

1.09(0.82–1.49)

Sisters

2.03(1.26–3.97)**

1.98(1.19–3.21)*

2.13(1.58–3.00)**

  1. * p < 0.05 ** p < 0.01
  2. a Excluded probands and spouses. b OR adjusted for family size, commune of residence, birth oder, total smoky coal exposure, pack-years of smoking, COPD history, education, age, sex and years of cooking.