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Figure 7 | BMC Cancer

Figure 7

From: Transformation of human bronchial epithelial cells alters responsiveness to inflammatory cytokines

Figure 7

Effect of OSM and macrophage factors on DNA synthesis of normal and abnormal epithelial cells. A, Normal epithelial cells (25 cultures) and B abnormal epithelial cells (8 metaplasia and 2 dysplasia) were treated with serially diluted OSM or conditioned macrophage medium and the incorporation of [3H]thymidine determined. All values expressed relative to the untreated cultures in each series. C, Paired cultures of normal and dysplastic epithelial cells (EC-65) were analyzed by immunoblotting for OSM-stimulated ERK phosphorylation and the same cells for inhibition of [3H]thymidine incorporation by OSM and macrophage-factors (mean and range of duplicate values)

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