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Table 2 Association between paternal and maternal ages at birth and risk of breast cancer in daughters

From: Association of paternal age at birth and the risk of breast cancer in offspring: a case control study

Age at birth of the subjects (yrs) Cases (%) Controls (%) OR (95% CI)1 OR (95% CI)2
Paternal age     
Mean ± SD 33.1 ± 7.5 32.5 ± 7.2 1.1 (1.00–1.28)  
<30 362 (35.8) 400 (39.6) 1.0 1.0
30–34 266 (26.3) 261 (25.8) 1.2 (0.92–1.45) 1.0 (0.79–1.34)
35–39 169 (16.7) 174 (17.2) 1.1 (0.83–1.40) 1.0 (0.71–1.39)
≥40 214 (21.2) 176 (17.4) 1.4 (1.07–1.76) 1.6 (1.04–2.32)
P for trend    0.025 0.090
Maternal age     
Mean ± SD 28.7 ± 6.4 28.3 ± 6.5 1.1 (0.97–1.28)  
<25 285 (28.2) 330 (32.6) 1.0 1.0
25–29 302 (29.9) 297 (29.4) 1.2 (0.97–1.54) 1.2 (0.95–1.56)
30–34 237 (23.4) 192 (19.0) 1.5 (1.18–1.95) 1.4 (1.00–1.94)
≥35 187 (18.5) 192 (19.0) 1.1 (0.88–1.48) 0.8 (0.55–1.27)
P for trend    0.079 0.998
  1. 1OR adjusted for family history of breast cancer in 1st or 2nd degree relatives and lifetime estrogen exposure duration
  2. 2OR adjusted for maternal age or paternal age (mutual parental age, categorical value) in addition to the variables in the model 1
  3. OR per 10 year