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Table 1 Selected characteristics for 1,011 breast cancer cases and 1,011 controls matched by year of birth and menopausal status

From: Association of paternal age at birth and the risk of breast cancer in offspring: a case control study

Risk factor

Cases (%)

Control (%)

OR (95% CI)

 

n = 1,011

n = 1,011

 

Age (yrs) (mean ± SD)

47.7 ± 10.9

47.7 ± 11.7

p = 0.984*

Education

   

Under or at middle school

315 (31.3)

319 (31.7)

1.0

At high school

378 (37.5)

407 (40.5)

1.0 (0.80–1.24)

At or over college

315 (31.3)

280 (27.8)

1.2 (0.98–1.57)

FHBC ‡

   

No

937 (92.7)

976 (96.5)

1.0

Yes

74 (7.3)

35 (3.5)

2.2 (1.47–3.38)

Age at FFTP ‡ (yrs) or nulliparity

   

<25

325 (32.2)

349 (34.9)

1.0

25–29

477 (47.3)

471 (47.1)

1.1 (0.92–1.38)

≥30 or nulliparity

206 (20.4)

181 (18.1)

1.3 (1.04–1.76)

P for trend

  

p = 0.027

LEE ‡ (yrs) (mean ± SD)

29.1 ± 6.9

28.3 ± 7.4

1.2 (1.05–1.41)†

BMI (kg/m 2 )

   

<25.0

748 (74.4)

769 (76.8)

1.0

25.0–29.9

227 (22.6)

216 (21.6)

1.0 (0.84–1.29)

≥30.0

31 (3.1)

16 (1.6)

2.0 (1.07–3.78)

Smoking status

   

Nonsmoker

933 (92.4)

943 (93.4)

1.0

Smoker

77 (7.6)

67 (6.6)

1.2 (0.85–1.70)

Alcohol drinking

   

<1/month

756 (74.8)

709 (72.3)

1.0

1–3/month

178 (17.6)

211 (21.5)

0.8 (0.64–1.02)

≥1/week

77 (7.6)

61 (6.2)

1.2 (0.86–1.76)

  1. OR of case vs. matched control adjusted for family history of breast cancer in 1st or 2nd degree relatives and lifetime estrogen exposure duration
  2. *P value by student t test, †OR per 10 year, ‡FHBC, Family history of breast cancer in 1st or 2nd degree relatives; FFTP, first full-term pregnancy; LEE, lifetime estrogen exposure duration