Table 1 Top twenty ranked genes

LSAMP

Limbic system associated membrane protein

-3.2 (-3.1)

1

Immunoglobulin superfamily member; cell adhesion

SLC38A2

Solute carrier family 38

-2.2 (-2.1)

2

Amino acid transporter A2, regulated by growth factors & hormones

CTAG1

Cancer/testis antigen 1

2.2 *(1.6, 1.5)

3

(see also Table 2)

MGC2780

Hypothetical protein

-2.2 (-5.5)

4

Unknown

§PCDH11Y

Proto-cadherin on the Y

-2.1 (-1.9)

5

Cell adhesion X chromosome homologue

PCSK4

Convertase; subtilisin/kexin 4

-2.0 (-1.6)

6

Cleave pro-hormones and pro-growth factors

ZADH1

Zinc-binding alcohol dehydrogenase domain containing protein

1.9 *(1.3, 1.2)

7

Alcohol dehydrogenase; possible retinoid metabolism

CD164

Cluster designation protein 164

-1.9 (-1.5)

8

Sialomucin, AKA, MGC-24

SFTPA2

Surfactant pulmonary associated protein

1.8 NC

9

Calcium dependent signalling innate immune response

FLJ23577

Hypothetical Kruppel-like protein

-1.8 NC

10

unknown

SR-BP1, OPRS1

Sterol binding protein Opoid receptor sigma

-1.7 NC

11

Sterol isomerase, ergosterol biosynthesis

FABP6

Fatty acid binding protein 6

-1.7 (-6.6)

12

Bile acid binding;

OR52P1

Olfactory receptor 52 pseudogene

1.7 NC

13

Pseudogene

CSTA

Cystatin A

-1.7 (-2.3)

14

Cysteine proteinase inhibitor

NPDC1

Neural differentiation & control protein

1.7 *(1.5, 1.3)

15

Inhibits proliferation

NXT2, P15-2

Nuclear transport factor 2-like export factor

1.7 NC

16

Exports RNA from nucleus

SECTM1

Secreted and transmembrane protein 1

-1.6 (-2.8)

17

Signal transduction activity with the NF-κB cascade

HKE2

HLA class II region KE2 gene

1.6 NC

18

Protein folding

NNMT

Nicotinamide N-methyltransferase

-1.6 (-4.6)

19

Methylates pyridines; biotransformation of drugs; enhanced in cancer cells

ZNF387, ST18

Zinc finger protein 387; breast cancer tumor suppressor

1.6 (2.7)

20

Transcription (see also Table 4)