Table 6 Summary of key findings in research for inflammatory breast cancer.
From: Short- and long-term cause-specific survival of patients with inflammatory breast cancer
Author | Ref. | Institute | Year | Patient No. | Main results |
|---|---|---|---|---|---|
Palangie | [21] | Institut Curie, France | 1977–1987 | 223 | Better DFS – rapid and complete remission with induction treatment |
Chang | [22] | MD Anderson, US | 1974–1993 | 177 | Shorter OS – for postmenopausal IBC women with larger body size |
Liauw | [3] | U. Florida, US | 1982–2001 | 61 | Improved CSS – tumor size <4 cm, upfront surgery, local disease control |
Perez | [23] | Mallinckrodt, US | 1958–1989 | 179 | Improved DFS, CSS, LR – addition of mastectomy |
Panades | [24] | British Columbia, Canada | 1980–2000 | 485 | Improved LC – mastectomy in addition to chemotherapy and radiotherapy |
Improved CSS – modern chemotherapy regimens | |||||
Fleming | [25] | MD Anderson, US | 1974–1993 | 178 | Improved LC – mastectomy in addition to radiotherapy 16.3% vs 35.7%, P = 0.015 |
Buchholz | [26] | MD Anderson, US | 1989–1997 | 12 | Chemotherapy with radiation improved OS |
Liao | [27] | MD Anderson, US | 1977–1993 | 115 | Improved LC, DFS, OS – twice-daily postmastectomy radiation to 66 Gy |
Bertucci | [28] | Institut Paoli-Calmettes, France | 1976–2000 | 74 | High-dose chemotherapy: 5y DFS 28%, OS 50% Conventional dose chemotherapy: 5y DFS 15%, OS 18% |
Ueno | [6] | MD Anderson, US | 1973–1993 | 178 | Improved DFS – combined modality: 15y DFS 28%, single-modality: 15y DFS <5% |