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Table 6 Summary of key findings in research for inflammatory breast cancer.

From: Short- and long-term cause-specific survival of patients with inflammatory breast cancer

Author Ref. Institute Year Patient No. Main results
Palangie [21] Institut Curie, France 1977–1987 223 Better DFS – rapid and complete remission with induction treatment
Chang [22] MD Anderson, US 1974–1993 177 Shorter OS – for postmenopausal IBC women with larger body size
Liauw [3] U. Florida, US 1982–2001 61 Improved CSS – tumor size <4 cm, upfront surgery, local disease control
Perez [23] Mallinckrodt, US 1958–1989 179 Improved DFS, CSS, LR – addition of mastectomy
Panades [24] British Columbia, Canada 1980–2000 485 Improved LC – mastectomy in addition to chemotherapy and radiotherapy
      Improved CSS – modern chemotherapy regimens
Fleming [25] MD Anderson, US 1974–1993 178 Improved LC – mastectomy in addition to radiotherapy 16.3% vs 35.7%, P = 0.015
Buchholz [26] MD Anderson, US 1989–1997 12 Chemotherapy with radiation improved OS
Liao [27] MD Anderson, US 1977–1993 115 Improved LC, DFS, OS – twice-daily postmastectomy radiation to 66 Gy
Bertucci [28] Institut Paoli-Calmettes, France 1976–2000 74 High-dose chemotherapy: 5y DFS 28%, OS 50% Conventional dose chemotherapy: 5y DFS 15%, OS 18%
Ueno [6] MD Anderson, US 1973–1993 178 Improved DFS – combined modality: 15y DFS 28%, single-modality: 15y DFS <5%
  1. DFS = disease free survival,
  2. OS = overall survival,
  3. CSS = cause-specific survival,
  4. LC = local recurrence.
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