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Table 2 Results of Cox proportional hazards models without transform. Hazard ratios (95% confidence intervals), values > 1 indicate increased risk of death.

From: Modeling the effect of age in T1-2 breast cancer using the SEER database

 

Overall mortality

Breast cancer specific mortality

 

N0

N+

N0

N+

SEER central area

1.00 (0.95–1.05)

0.93 (0.87–0.98)

1.03 (0.94–1.13)

0.92 (0.86–0.99)

SEER western area

0.92 (0.88–0.97)

0.87 (0.82–0.92)

0.82 (0.75–0.90)

0.86 (0.80–0.91)

Race black

1.38 (1.27–1.49)

1.42 (1.31–1.52)

1.37 (1.21–1.55)

1.44 (1.31–1.57)

Married

0.75 (0.72–0.78)

0.82 (0.78–0.86)

0.88 (0.81–0.95)

0.91 (0.86–0.97)

Inner quadrant

1.09 (1.04–1.15)

1.16 (1.08–1.24)

1.32 (1.21–1.44)

1.3 (1.19–1.41)

Ductal histology

1.14 (1.09–1.2)

1.11 (1.04–1.17)

1.44 (1.31–1.58)

1.12 (1.05–1.21)

ER negative

1.39 (1.28–1.5)

1.52 (1.41–1.64)

1.58 (1.4–1.78)

1.58 (1.44–1.73)

PR negative

1.11 (1.03–1.18)

1.27 (1.18–1.36)

1.36 (1.21–1.52)

1.39 (1.28–1.52)

Grade 3–4

1.23 (1.17–1.29)

1.34 (1.28–1.41)

1.6 (1.48–1.73)

1.48 (1.39–1.57)

BCS

1.12 (1.02–1.24)

0.96 (0.86–1.07)

1.01 (0.84–1.20)

0.98 (0.86–1.12)

Radiotherapy

1.12 (0.96–1.29)

0.89 (0.83–0.95)

1.31 (1.08–1.6)

0.91 (0.84–0.99)

BCSxRT

0.61 (0.51–0.73)

0.92 (0.8–1.06)

0.63 (0.48–0.82)

0.88 (0.74–1.04)

Year Diagnosis (continuous, year)

0.98 (0.97–0.99)

0.96 (0.95–0.97)

0.92 (0.91–0.94)

0.94 (0.93–0.95)

Age at Diagnosis (continuous, year)

1.05 (1.05–1.05)

1.02 (1.02–1.03)

1.00 (1.00–1.01)

1.00 (1.00–1.01)

Tumor size (continuous, mm)

1.03 (1.03–1.03)

1.02 (1.02–1.02)

1.05 (1.04–1.05)

1.02 (1.02–1.03)

Number positive nodes (continuous, n)

(-)

1.07 (1.07–1.08)

(-)

1.09 (1.08–1.09)

Number nodes examined (continuous, n)

0.99 (0.99–0.99)

0.98 (0.97–0.98)

0.99 (0.99–1.00)

0.97 (0.96–0.97)

  1. BCS = breast conserving surgery, BCSxRT = breast conserving surgery and radiotherapy, ER = estrogen receptor, N0 = node negative, N+ = node positive, PR = progesterone receptor, SEER = Surveillance, Epidemiology, and End Results Program.