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Table 1 Summary of relationship between VEGF isoform expression and pathologic features in colorectal and non-small cell lung cancers (p < 0.05 was considered significant)

From: Alteration of protein expression pattern of vascular endothelial growth factor (VEGF) from soluble to cell-associated isoform during tumourigenesis

Pathologic features VEGF isoform (kDa)
  VEGF 23 kDa p valuea VEGF 26 kDa p valuea
Colorectal cancer (total 76 cases) 42 (55.3%)   53 (69.7%)  
Gender     
   Female (46 cases) 28 (60.8%) 0.224 32 (69.5%) 0.968
   Male (30 cases) 14 (46.7%)   21 (70.0%)  
Tumour size     
   ≤ 5 cm (45 cases) 30 (66.7%)b < 0.05 30 (66.7%) 0.483
   > 5 cm (31 cases) 12 (38.7%)   23 (74.1%)  
Histological differentiation     
   Well (42 cases) 22 (52.4%) 0.574 28 (66.7%) 0.517
   Moderate or Poor (34 cases) 20 (58.8%)   25 (73.5%)  
Tumour stage grouping     
   Early stage (I or II) (34 cases) 23 (67.6%) 0.09 19 (55.9%) < 0.01
   Late stage (III or IV) (42 cases) 19 (45.2%)   34 (80.9%)  
Metastasis     
   No (49 cases) 31 (63.3%) 0.059 29 (59.2%) < 0.01
   Yes (27 cases) 11 (40.7%)   24 (88.9%)  
Lung cancer (total 18 cases) 16 (88.9%)   16 (88.9%)  
Gender     
   Female (10 cases) 8 (80.0%) 0.477 8 (80.0%) 0.477
   Male (8 cases) 8 (100.0%)   8(100%)  
Tumour size     
   ≤ 5 cm (7 cases) 7 (100.0%) 0.231 7 (100.0%) 0.231
   > 5 cm (11 cases) 9 (81.8%)   9 (81.8%)  
Histological differentiation     
   Well (5 cases) 4 (80.0%) 0.490 4 (80.0%) 0.490
   Moderate or Poor (13 cases) 12 (92.3%)   12 (93.3%)  
Tumour stage grouping     
   Early stage (I or II) (2 cases) 1 (50.0%) 0.210 0 (0.0%) < 0.01
   Late stage (III or IV) (16 cases) 15 (93.8%)   16 (100%)  
Metastasis     
   No (7 cases) 6 (85.7%) 1.00 5 (71.4%) 0.137
   Yes (11 cases) 10 (90.9%)   11 (100.9%)  
  1. a chi-square test, b percentage in relation to total number of cases in each pathological features