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Figure 3 | BMC Cancer

Figure 3

From: Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer

Figure 3

Kinase inhibitors block activation at multiple points in EGFR/AP-1 pathway. Inhibitors decrease the response of the AP-1-bla ME180 CellSensor when stimulated with EGF. β-lactamase was measured using Invitrogen's LiveBLAzer™ assay (Panel A). Percent inhibition is determined in comparison to untreated sample and represents the mean of (± SEM) eight independent data points (n = 8). Photomicrographs of cells were obtained under fluorescent microscopy (Panel B).

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