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Table 1 Comparison of mast cell numbers in tumors and corresponding normal tissues.

From: Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts

  Mean Numbers of Mast Cells/40 × Field (± 1 standard deviation)
  Peri-tumoral tissue Core of tumor Normal tissue
Breast (n = 10) 4.9 ± 1.1 0.3 ± 0.3* 1.2 ± 0.9**
Head & neck (n = 10) 6.7 ± 3.6 0.5 ± 0.3* 2.8 ± 2.1**
Ovarian (n = 10) 3.0 ± 0.8 0.7 ± 0.6* 0.9 ± 0.8**
Lung (n = 10) 4.4 ± 1.9 1.0 ± 0.3* 2.5 ± 0.6 **
Non-Hodgkins (n = 5) 2.1 ± 1.0 1.8 ± 0.5 NS 1.0 ± 0.5 NS
Hodgkin's (n = 8) 4.3 ± 1.3 1.9 ± 0.8* 1.0 ± 0.5**
  1. *p value < 0.05, comparing mean numbers of mast cells in core of tumor versus per-tumoral regions.
  2. ** p value < 0.05, comparing mean numbers of mast cells in normal tissue counterparts (n = 3) to peri-tumoral tissue.