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Table 1 Comparison of mast cell numbers in tumors and corresponding normal tissues.

From: Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts

 

Mean Numbers of Mast Cells/40 × Field (± 1 standard deviation)

 

Peri-tumoral tissue

Core of tumor

Normal tissue

Breast (n = 10)

4.9 ± 1.1

0.3 ± 0.3*

1.2 ± 0.9**

Head & neck (n = 10)

6.7 ± 3.6

0.5 ± 0.3*

2.8 ± 2.1**

Ovarian (n = 10)

3.0 ± 0.8

0.7 ± 0.6*

0.9 ± 0.8**

Lung (n = 10)

4.4 ± 1.9

1.0 ± 0.3*

2.5 ± 0.6 **

Non-Hodgkins (n = 5)

2.1 ± 1.0

1.8 ± 0.5 NS

1.0 ± 0.5 NS

Hodgkin's (n = 8)

4.3 ± 1.3

1.9 ± 0.8*

1.0 ± 0.5**

  1. *p value < 0.05, comparing mean numbers of mast cells in core of tumor versus per-tumoral regions.
  2. ** p value < 0.05, comparing mean numbers of mast cells in normal tissue counterparts (n = 3) to peri-tumoral tissue.